Tocris™ 968

Allosteric inhibitor of glutaminase

Manufacturer: Tocris™ 5460/10

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Catalog No. 54-601-0

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For Research Use Only


    Quantity 10mg
    Molecular Weight 475.42
    Purity >99
    Description 968
    Product Type 968

    Allosteric inhibitor of glutaminase. Blocks Rho-GTPase-dependent transformation of fibroblasts. Suppresses breast cancer cell growth and invasive activity in vitro. Also inhibits P-493 B lymphoma cell growth and reduces tumor size of P-493 cell xenografts in mice.

    • Chemical Name: 5-[3-Bromo-4-(dimethylamino)phenyl]-2,3,5,6-tetrahydro-2,2-dimethylbenzo[a]phenanthridin-4(1H)-one
    • Formula: C27H27BrN2O
    • CAS Number: 311795-38-7
    • Solubility: Soluble to 20mM in DMSO
    • Purity: >99

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