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Tocris Bioscience™ A 410099.1, amine
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Catalog No. 6471100
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Quantity:
100 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Functionalized IAP ligand for PROTACs

A 410099.1, amine is a functionalized IAP ligand for PROTAC® research and development. Boc protected A 410099.1 (Cat.No. 6470). Supplied with an amine functional handle for ready conjugation to a linker/target protein ligand. NanoBRET assays show EC50 values of 4.6, 9.2 and 15.6 nM for cIAP1, cIAP2 and XIAP proteins, respectively. Part of a range of functionalized tool molecules for PROTAC R&D. Please contact us for SD files of our available Degrader Building Blocks. PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Specifications

Chemical Name or Material tert-Butyl [(S)-1-[[(S)-2-[(2S,4S)-4-amino-2-[[(R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]pyrrolidin-1-yl]-1-cyclohexyl-2-oxoethyl]amino]-1-oxopropan-2-yl](methyl)carbamate hydrochloride
CAS 2374122-37-7
Quantity 100 mg
Molecular Formula C32H49N5O5.HCl
Purity 98%
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