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  5. Tocris Bioscience™ A 438079 hydrochloride

Tocris Bioscience™ A 438079 hydrochloride
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Catalog No. 297250
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Competitive P2X7 antagonist

A 438079 hydrochloride is a competitive P2X7 receptor antagonist (pIC50 = 6.9 for the inhibition of Ca2+ influx in the human recombinant P2X7 cell line). Devoid of activity at other P2 receptors (IC50 > 10 μM). Possesses antinociceptive activity in models of neuropathic pain in vivo. Inhibits methamphetamine-induced microglial migration and phagocytosis in vitro.

Chemical Identifiers

CAS 899431-18-6
Molecular Formula C13H10Cl3N5

Specifications

Quantity 50 mg
Formula Weight 342.61
Purity >98%
Molecular Weight (g/mol) 342.608
Chemical Name or Material A 438079 hydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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