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Tocris Bioscience™ A 740003
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Catalog No. 370150R
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Catalog No. Quantity
37-015-0R 50 mg
37-011-0R 10 mg
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Catalog No. 37-015-0R Supplier Tocris Bioscience™ Supplier No. 3701/50
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Description

Potent and selective P2X7 antagonist

A 740003 is a potent and selective P2X7 receptor antagonist (IC50 values are 18 and 40 nM for rat and human receptors respectively). Displays selectivity over a variety of P2X and P2Y receptors up to a concentration of 100 μM. Reduces nociception in animal models of persistent neuropathic and inflammatory pain. Also reduces neuroblastoma tumor growth in mice.

Specifications

Quantity 50 mg
Product Type A 740003
Purity >98%
Molecular Weight (g/mol) 474.55
Inhibitors A 740003

For Research Use Only

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