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Tocris Bioscience™ A 971432

Potent and selective S1P5 agonist

Supplier:  Tocris Bioscience™ 5766/50

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Catalog No. 57-665-0


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Description

Description

A 971432 is a potent and selective S1P5 agonist (EC50 values are 4.1 and 5.7 nM in cAMP and GTPγS assays, respectively). Exhibits 60-fold selectivity over S1P1, and >1,600-fold selectivity over S1P2-4, and a panel of 129 kinases and 79 receptors. Improves blood-brain barrier integrity in vitro and reverses age-related cognitive decline in vivo. Orally available.
Specifications

Specifications

1-[[4-[(3,4-Dichlorophenyl)methoxy]phenyl]methyl]-3-azetidinecarboxylic acid
50 mg
C18H17Cl2NO3
>99%
1240308-45-5
Sphingosine-1-phosphate Receptor Agonists
366.24
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Safety and Handling

Safety and Handling

Recommended Storage : Store at Room Temperature

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