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Invitrogen™ A2M Monoclonal Antibody (F1-P1C11 #3)
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Catalog No. PIMA514663
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100 μg
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Catalog No. Quantity
PIMA514663 100 μg
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Catalog No. PIMA514663 Supplier Invitrogen™ Supplier No. MA514663
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Description

Mouse Monoclonal Antibody

MA5-14663 targets Alpha2-Macroglobulin in ELISA, IP, and RIA applications and shows reactivity with Human samples. The MA5-14663 immunogen is purified human plasma AMG. MA5-14663 detects Alpha2-Macroglobulin which has a predicted molecular weight of approximately 162 kDa. Product MA514663 is a smaller package size of MIA1201 (formerly sold as a Seradyn product).

Alpha 2-Macroglobulin (a2M), is a approximately 720-kDa homotetrameric glycoprotein composed of four identical approximately 180 kDa subunits. aAlpha 2M shares with other alpha-macroglobulins, like the complement components C3 and C4 and the pregnancy zone protein PZP, an extraordinary binding capacity for a variety of ligands. This allows the alpha-macroglobulins to serve as humoral defense barriers against foreign peptides in the plasma. Alpha 2M interacts and captures virtually any proteinase, often referred to as a panprotease inhibitor. In the brain of Alzheimer's disease (AD) patients, Alpha 2M also has been localized to diffuse amyloid plaques, supporting an important role for alpha 2M in AD etiopathology.
TRUSTED_SUSTAINABILITY

Specifications

Antigen A2M
Applications ELISA, Immunoprecipitation, Radioimmune Assays (RIA), Western Blot
Classification Monoclonal
Clone F1-P1C11 #3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA and 0.05% sodium azide
Gene A2M
Gene Accession No. P01023
Gene Alias A2M; A2m1; A2maa; A2MAC1; A2MD; A2mp; Alpha 2 M; Alpha-2-M; Alpha-2-M (A2M); alpha-2-macroglobulin; Alpha-2-macroglobulin-P; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5; CPAMD5; DKFZp779B086; FWP007; LOC100061656; Mam; S863 7; S863-7
Gene Symbols A2M
Host Species Mouse
Immunogen Purified human plasma AMG.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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