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AMPK alpha 1 Rabbit anti-Bovine, Human, Rat, Polyclonal, Bethyl Laboratories Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Bethyl Laboratories, IncSupplier Diversity Partner A300507AT

Catalog No. 50-155-7784


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Description

Description

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval is not recommended. Based on 100% sequence identity, this antibody is predicted to react with Mouse and Orangutan

AMPKa belongs to the family of AMP activated protein kinases, that plays a central role in regulating cellular and organismal energy balance in response to the balance between AMP/ATP, and intracellular Ca2+ levels. AMPK exists as a heterotrimer comprising of catalytic alpha subunit, and regulatory beta and gamma subunits. The alpha subunit is activated by increases in the cellular AMP:ATP ratio caused by metabolic stresses, and can mediate the effects of the adipokines leptin and adiponectin. Two isoforms differ in subcellular localization and AMP-dependence. Phosphorylation of threonine 172 in the alpha subunit is a key determit of AMPK activity.
Specifications

Specifications

AMPK alpha 1
Polyclonal
Unconjugated
PRKAA1
liquid
Prkaa1
Between 350 and 400
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Bovine, Human, Rat
Immunohistochemistry, Western Blot
1 mg/ml
TBS with 0.1% BSA and 0.09% sodium azide
P54645, Q13131
AMPK, AMPKa1, MGC33776, MGC57364
Rabbit
IgG
10 μl
4° C
Primary
540404, 5562, 65248
SDS
Documents
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