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AMPK alpha 1 Rabbit anti-Bovine, Human, Rat, Polyclonal, Bethyl Laboratories
Rabbit Polyclonal Antibody
Supplier: Bethyl Laboratories, Inc A300507AT
Description
The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval is not recommended. Based on 100% sequence identity, this antibody is predicted to react with Mouse and Orangutan
AMPKa belongs to the family of AMP activated protein kinases, that plays a central role in regulating cellular and organismal energy balance in response to the balance between AMP/ATP, and intracellular Ca2+ levels. AMPK exists as a heterotrimer comprising of catalytic alpha subunit, and regulatory beta and gamma subunits. The alpha subunit is activated by increases in the cellular AMP:ATP ratio caused by metabolic stresses, and can mediate the effects of the adipokines leptin and adiponectin. Two isoforms differ in subcellular localization and AMP-dependence. Phosphorylation of threonine 172 in the alpha subunit is a key determit of AMPK activity.Specifications
AMPK alpha 1 | |
Polyclonal | |
Unconjugated | |
PRKAA1 | |
AMPK, AMPKa1, MGC33776, MGC57364 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
540404, 5562, 65248 | |
4° C | |
Liquid |
Immunohistochemistry, Western Blot | |
1 mg/ml | |
TBS with 0.1% BSA and 0.09% sodium azide | |
P54645, Q13131 | |
Prkaa1 | |
Between 350 and 400 | |
10 μL | |
Primary | |
Bovine, Human, Rat | |
Antibody | |
IgG |
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