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  5. Tocris Bioscience™ AA 147

Tocris Bioscience™ AA 147
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Catalog No. 675925
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Quantity:
5 mg
25 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

ER proteostasis regulator

AA 147 is an endoplasmic reticulum (ER) proteostasis regulator. Activates the ATF6 transcriptional program independently of ER stress and/or global UPR activation. Selectively reduces secretion of amyloidogenic transthyretin (TTR) from HepG2 cells. Reduces amyloidogenic immunoglobulin light chain (ALLC) secretion from ALMC-2 cells (EC50 = 1.1 μM).

Specifications

Chemical Name or Material N-(2-Hydroxy-5-methylphenyl)benzenepropanamide
CAS 393121-74-9
Quantity 25 mg
Molecular Formula C16H17NO2
Formula Weight 255.31
Purity 98%
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