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  5. Tocris Bioscience™ AA 147

Tocris Bioscience™ AA 147
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Catalog No. 675925
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25 mg
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Catalog No. Quantity
67-592-5 25 mg
67-595 5 mg
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Catalog No. 67-592-5 Supplier Tocris Bioscience™ Supplier No. 6759/25
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Description

ER proteostasis regulator

AA 147 is an endoplasmic reticulum (ER) proteostasis regulator. Activates the ATF6 transcriptional program independently of ER stress and/or global UPR activation. Selectively reduces secretion of amyloidogenic transthyretin (TTR) from HepG2 cells. Reduces amyloidogenic immunoglobulin light chain (ALLC) secretion from ALMC-2 cells (EC50 = 1.1 μM).

Specifications

Chemical Name or Material N-(2-Hydroxy-5-methylphenyl)benzenepropanamide
CAS 393121-74-9
Quantity 25 mg
Molecular Formula C16H17NO2
Formula Weight 255.31
Purity 98%
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