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AADACL2 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550286

Catalog No. PA550286


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Description

Description

The antibody detects endogenous levels of total AADACL2 protein.

AADAC is a 45 kDa membrane-associated hydrolase highly expressed in the human liver that has been implicated in the hydrolysis of arylacetamide xenobiotics including flutamide and phenacetin.556-560AADAC is highly homologous to several related lipases, AADACL1, 2, and 4, the latter two of which remain completely unotated. Overexpression of AADAC in a rat hepatoma cell line produces changes in cellular TG levels, apoplipoprotein B secretion, and fatty acid oxidation, but the mechanism for these effects remains unclear. 561 Candidate endogenous substrates, selective inhibitors, or knockout mice have not, to our knowledge, been described for AADAC or the related enzymes AADACL2 and AADACL4.
Specifications

Specifications

AADACL2
Polyclonal
Unconjugated
AADACL2
Liquid
AADACL2
Fusion protein corresponding to residues near the C terminal of human arylacetamide deacetylase-like 2
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin)
1.1 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
Q6P093
ADCL2,MGC72001, Arylacetamide deacetylase-like 2,
Rabbit
IgG
100 μL
-20°C
Primary
344752
Documents
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