AADACL2 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA550286
The antibody detects endogenous levels of total AADACL2 protein.AADAC is a 45 kDa membrane-associated hydrolase highly expressed in the human liver that has been implicated in the hydrolysis of arylacetamide xenobiotics including flutamide and phenacetin.556-560AADAC is highly homologous to several related lipases, AADACL1, 2, and 4, the latter two of which remain completely unotated. Overexpression of AADAC in a rat hepatoma cell line produces changes in cellular TG levels, apoplipoprotein B secretion, and fatty acid oxidation, but the mechanism for these effects remains unclear. 561 Candidate endogenous substrates, selective inhibitors, or knockout mice have not, to our knowledge, been described for AADAC or the related enzymes AADACL2 and AADACL4.
|Fusion protein corresponding to residues near the C terminal of human arylacetamide deacetylase-like 2|
|Antigen affinity chromatography|
|PBS with 50% glycerol and 0.05% sodium azide; pH 7.3|
|ADCL2,MGC72001, Arylacetamide deacetylase-like 2,|
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