Invitrogen™ AADACL2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550286

Catalog No. PA550286

Description

The antibody detects endogenous levels of total AADACL2 protein.

AADAC is a 45 kDa membrane-associated hydrolase highly expressed in the human liver that has been implicated in the hydrolysis of arylacetamide xenobiotics including flutamide and phenacetin.556-560AADAC is highly homologous to several related lipases, AADACL1, 2, and 4, the latter two of which remain completely unannotated. Overexpression of AADAC in a rat hepatoma cell line produces changes in cellular TG levels, apoplipoprotein B secretion, and fatty acid oxidation, but the mechanism for these effects remains unclear. 561 Candidate endogenous substrates, selective inhibitors, or knockout mice have not, to our knowledge, been described for AADAC or the related enzymes AADACL2 and AADACL4.

Specifications

• Antigen: AADACL2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: AADACL2
• Gene Alias: Aadacl2; ADCL2; arylacetamide deacetylase like 2; arylacetamide deacetylase-like 2; EG639634; MGC72001; RGD1563197
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 344752
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q6P093
• Gene Symbols: AADACL2
• Immunogen: Fusion protein corresponding to residues near the C terminal of human arylacetamide deacetylase-like 2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG