Invitrogen™ AADAT Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588974

Catalog No. PIPA588974

Description

Immunogen sequence: PKSMISLAGG LPNPNMFPFK TAVITVENGK TIQFGEEMMK RALQYSPSAG IPELLSWLKQ LQIKLHNPPT IHYPPSQGQM DLCVTSGSQQ GLCKVFEMII NPGDNVLLDE PAYSGTLQSL HPLGCNIINV ASDESGIVPD SLRDILSRWK PEDAKNPQKN TPKFLYTVPN GNNPTGNSLT SERKKEIYEL ARKYDFLIIE DDPYYFLQFN KFRVPTFLSM DVDGRVIRAD SFSKIISSGL RIGFLTGPKP LIERVILHIQ VSTLHPSTFN QLMISQLLHE WGEEGFMAHV DRVIDFYSNQ KDAILAAADK WLTGLAEWHV PAAGMFLWIK VKGINDVKEL IEEKAVKMGV LMLPGNAFYV DSSAPSPYLR ASFSSASPEQ MDVAFQVLAQ LIKESL; Positive Samples: Mouse liver, Rat kidney; Cellular Location: Mitochondrion.

This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Two alternative transcripts encoding the same isoform have been identified, however, additional alternative transcripts and isoforms may exist.

Specifications

• Antigen: AADAT
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Aadat
• Gene Alias: 2-aminoadipate aminotransferase; 2-aminoadipate transaminase; AadAT; Aadt; AI875679; alpha-aminoadipate aminotransferase; aminoadipate aminotransferase; KAT/AadAT; Kat2; KATII; KYAT2; kynurenine aminotransferase 2; kynurenine aminotransferase II; kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; kynurenine--oxoglutarate; Kynurenine--oxoglutarate aminotransferase II; kynurenine--oxoglutarate transaminase 2; Kynurenine--oxoglutarate transaminase II; L kynurenine/alpha aminoadipate aminotransferase; mKat-2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23923, 29416, 51166
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1.38 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q64602, Q8N5Z0, Q9WVM8
• Gene Symbols: Aadat
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 34-429 of human AADAT (NP_0012736111).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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