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Invitrogen™ AANAT Polyclonal Antibody
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Catalog No. PIPA526631
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400 μL
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Catalog No. Quantity
PIPA526631 400 μL
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Catalog No. PIPA526631 Supplier Invitrogen™ Supplier No. PA526631
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Description

Rabbit Polyclonal Antibody

PA5-26631 has successfully been used to detect serotonin N-AT in both WB and IF applications.

Arylalkylamine N-Acetyltransferase (AANAT) is the penultimate enzyme is melatonin synthesis. Hormonal melatonin has been implicated in sleep and circadian clock function. Large changes in the abundance of AANAT are believed to be responsible for the large day/night rhythms in melatonin synthesis in the pineal gland and retina. Most research shows that AANAT activity is regulated by controlling the steady-state levels of the protein. Recent research, however, suggests that another mechanism may also play a role in controlling melatonin production without altering AANAT protein and activity. This mechanism may explain the sudden physiological increase in circulating melatonin observed at the onset of the dark period in humans.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AANAT
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene Aanat
Gene Accession No. Q16613
Gene Alias Aanat; AA-NAT; Aralkylamine N-acetyltransferase; arylakylamine N-acetyltransferase; Arylalkylamine N - acetyltransferase (Serotonin N - acetyltransferase); arylalkylamine N-acetyltransferase; DSPS; Nat-2; Nat4; Seretonin N-acetyltransferase; serotonin acetylase; Serotonin N-acetyltransferase; SNAT
Gene Symbols Aanat
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 27-54 amino acids from the N-terminal region of human AANAT.
Purification Method Antigen Affinity Chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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