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  5. Tocris Bioscience™ AAQ Chloride

Tocris Bioscience™ AAQ Chloride

Catalog No. 546210
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Catalog No. 546210 Supplier Tocris Bioscience™ Supplier No. 5462/10
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Description

Photoswitchable Kv channel blocker

AAQ chloride is a photoswitchable Kv channel blocker (IC50 values are 2 and 64 μM at 500 nm and 380 nm respectively). Switches conformation from cis to trans at 500 nm and trans to cis at 380 nm. Exhibits minimal activity at Nav1.2 and L-type Ca2+ channels. Stimulates action potential firing of hippocampal neurons in vitro at 500 nm and restores visual responsiveness in blind mice at 380 nm.

Specifications

Chemical Name or Material N,N,N-Triethyl-2-oxo-2-[[4-[2-[4-[(1-oxo-2-propen-1-yl)amino]phenyl]diazenyl]phenylamino]ethanaminium chloride
Assay Percent Range >98%
Quantity 10 mg
Solubility Soluble to 20mM in DMSO
Molecular Formula C23H30ClN5O2
Formula Weight Observed MW: 443.97

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