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Invitrogen™ AARS2 Polyclonal Antibody
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Catalog No. PIPA557347
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100 μL
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PIPA557347 100 μL
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Catalog No. PIPA557347 Supplier Invitrogen™ Supplier No. PA557347
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: THLLNWALRQ TLGPGTEQQG SHLNPEQLRL DVTTQTPLTP EQLRAVENTV QEAVGQDEAV YMEEVPLALT AQVP Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 81%.

The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AARS2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene AARS2
Gene Accession No. Q5JTZ9
Gene Alias AARS2; AARSL; alanine tRNA ligase 2, mitochondrial (putative); alanine--tRNA ligase, mitochondrial; alanine--tRNA ligase, mitochondrial {ECO:0000255; Alanyl-tRNA synthetase; alanyl-tRNA synthetase {ECO:0000255; alanyl-tRNA synthetase 2, mitochondrial; alanyl-tRNA synthetase 2, mitochondrial (putative); alanyl-tRNA synthetase like; alanyl-tRNA synthetase, mitochondrial; alaRS; alaRS {ECO:0000255; bA444E17.1; COXPD8; Gm89; HAMAP-Rule:MF_03133}; Kiaa1270; LKENP; MTALARS; MT-ALARS; probable alanyl-tRNA synthetase, mitochondrial
Gene Symbols AARS2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human AARS2. Recombinant protein control fragment (Product #RP-94748).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57505
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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