Invitrogen™ AASS Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA554262

Catalog No. PIPA554262

Description

Immunogen sequence: MLQVHRTGLG RLGVSLSKGL HHKAVLAVRR EDVNAWERRA PLAPKHIKGI TNLGYKVLIQ PSNRRAIHDK DYVKAGGILQ EDISEACLIL GVKRPPEEKL MSRKTYAFFS HTIKAQEANM GLLDEILKQE IR Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 84%.

AASS is a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in the gene encoding this protein are associated with familial hyperlysinemia.

Specifications

• Antigen: AASS
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: AASS
• Gene Alias: AASS; aass {ECO:0000312; alpha-aminoadipate semialdehyde synthase; alpha-aminoadipic semialdehyde synthase, mitochondrial; aminoadipate-semialdehyde synthase; aminoadipic semialdehyde synthase; EMBL:AAI28772.1}; LKR; LKR/SDH; LKRSDH; LOR; LOR/SDH; Lorsdh; Lysine ketoglutarate reductase; lysine oxoglutarate reductase; lysine-2-oxoglutarate reductase; lysine-ketoglutarate reductase /saccharopine dehydrogenase; saccharopine dehydrogenase; SDH
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10157, 296925, 30956
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: A2VCW9, Q99K67, Q9UDR5
• Gene Symbols: AASS
• Immunogen: Recombinant protein corresponding to Human AASS. Recombinant protein control fragment (Product #RP-92606).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov