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ABAT Mouse anti-Human, Clone: OTI6C9, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF806968

Encompass_Preferred

Catalog No. 50-166-8055


May include imposed supplier surcharges.
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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

ABAT (4-aminobutyrate aminotransferase) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codomit alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
Specifications

Specifications

ABAT
Monoclonal
Unconjugated
ABAT
GABA-AT, GABAT, NPD009
Mouse
Affinity Chromatography
RUO
18
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Immunohistochemistry (Paraffin), Western Blot
OTI6C9
PBS with 8% trehalose and no preservative; pH 7.3
P80404
ABAT
Human recombit protein fragment corresponding to amino acids 29-323 of human ABAT produced in E.coli.
100 μg
Primary
Human
Antibody
IgG1
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