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Invitrogen™ ABCA1 Polyclonal Antibody, DyLight™ 488
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Catalog No. PIPA522908
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100 μL
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PIPA522908 100 μL
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Catalog No. PIPA522908 Supplier Invitrogen™ Supplier No. PA522908
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Description

Rabbit Polyclonal Antibody

ABCA1 Polyclonal Antibody for ChIP, ELISA, EMSA, Flow, ICC/IF, IHC (F), IHC (P), IP, ISH, Neu, Western Blot

Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) have been reported in Tangier disease (TD). TD is an autosomal recessive disorder characterized by an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and deviations in cellular lipid trafficking. ABCA1 mediates the apo-A1 associated export of cholesterol and phospholipids from the cell. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ABCA1
Applications ChIP Assay, ELISA, Flow Cytometry, Gel Shift, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, In Situ Hybridization (ISH), Neutralization, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.68 mg/mL
Conjugate DyLight 488
Formulation 50mM sodium borate with 0.05% sodium azide
Gene Abca1
Gene Accession No. O95477, P41233
Gene Alias ABC 1; ABC 1 antibody; ABC Transporter 1; Abc1; ABC-1; ABC1 antibody; Abca1; ATP binding cassette subfamily A member 1; ATP-binding cassette 1; ATP-binding cassette sub-family A member 1; ATP-binding cassette transporter 1; ATP-binding cassette transporter A1; ATP-binding cassette, subfamily A (ABC1), member 1; ATP-binding cassette, sub-family A (ABC1), member 1; ATP-binding cassette, sub-family A member 1; CERP; CERP antibody; Cholesterol efflux regulatory protein; HDLDT1; membrane-bound; phospholipid-transporting ATPase ABCA1; phospholipid-transporting ATPase ABCA1; ATP-binding cassette sub-family A member 1; TGD
Gene Symbols Abca1
Host Species Rabbit
Immunogen Partial peptide sequence (within residues 1100-1300) of human ABCA1.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100054241, 100152112, 100356765, 100761226, 11303, 19, 313210, 373945, 481651
Target Species Canine, Chicken, Horse, Hamster, Human, Mustelid, Mouse, Monkey, Pig, Rabbit, Rat
Content And Storage 4°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG
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