Invitrogen™ ABCA1 Polyclonal Antibody, DyLight™ 550

Catalog No.	Quantity
PIPA522910	100 μL

Catalog No. PIPA522910 Supplier Invitrogen™ Supplier No. PA522910

Description

Rabbit Polyclonal Antibody

ABCA1 Polyclonal Antibody for Western Blot, IHC (P), IHC (F), ICC/IF, Flow, ELISA, IP, ChIP, Neu, GS, ISH

Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) have been reported in Tangier disease (TD). TD is an autosomal recessive disorder characterized by an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and deviations in cellular lipid trafficking. ABCA1 mediates the apo-A1 associated export of cholesterol and phospholipids from the cell. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI.

Specifications

• Antigen: ABCA1
• Applications: ChIP Assay, ELISA, Flow Cytometry, Gel Shift, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, In Situ Hybridization (ISH), Neutralization, Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.93 mg/mL
• Conjugate: DyLight 550
• Formulation: 50mM sodium borate with 0.05% sodium azide
• Gene: Abca1
• Gene Accession No.: O95477, P41233
• Gene Alias: ABC 1; ABC 1 antibody; ABC Transporter 1; Abc1; ABC-1; ABC1 antibody; Abca1; ATP binding cassette subfamily A member 1; ATP-binding cassette 1; ATP-binding cassette sub-family A member 1; ATP-binding cassette transporter 1; ATP-binding cassette transporter A1; ATP-binding cassette, subfamily A (ABC1), member 1; ATP-binding cassette, sub-family A (ABC1), member 1; ATP-binding cassette, sub-family A member 1; CERP; CERP antibody; Cholesterol efflux regulatory protein; HDLDT1; membrane-bound; phospholipid-transporting ATPase ABCA1; phospholipid-transporting ATPase ABCA1; ATP-binding cassette sub-family A member 1; TGD
• Gene Symbols: Abca1
• Host Species: Rabbit
• Immunogen: Partial peptide sequence (within residues 1100-1300) of human ABCA1.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 100054241, 100152112, 100356765, 100761226, 11303, 19, 313210, 373945, 481651
• Target Species: Human, Mouse, Rat, Canine, Rabbit, Monkey, Hamster, Pig, Horse, Chicken, Mustelid
• Content And Storage: 4°C, store in dark
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG