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Invitrogen™ ABCA5 Polyclonal Antibody
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Catalog No. PIPA542402
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100 μL
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PIPA542402 100 μL
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Catalog No. PIPA542402 Supplier Invitrogen™ Supplier No. PA542402
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Description

Rabbit Polyclonal Antibody

Peptide sequence: HKEYDDKKDF LLSRKVKKVA TKYISFCVKK GEILGLLGPN GAGKSTIINI Sequence homology: Cow: 79%; Dog: 86%; Horse: 86%; Human: 100%; Mouse: 93%; Rabbit: 86%; Rat: 93%.

ABCA5 (ATP-binding cassette, sub-family A (ABC1), member 5) is a 1,642 amino acid protein belonging to the ABC transporter superfamily and the ABCA family. The ABC1 subfamily is the only major ABC subfamily exclusive to multicellular eukaryotes. Ubiquitously expressed, with high expression in testis, skeletal muscle, kidney, liver and placenta, ABCA5 is a multi-pass membrane protein that contains two ABC transporter domains and exists as three alternatively spliced isoforms. ABCA5 exhibits membrane subcellular localization and may play a role in processing autolysosomes. Spanning 80 kb, ABCA5 contains 39 exons, with exon 2 containing the putative translation start site. ABCA5 is the first of five ABC1 family members that maps to human chromosome 17q24. ABCA5 is linked to lysosomal diseases and may play a role in tumor development and cardiomyocyte and follicular cell activities. ABCA5 might also be a specific urine marker for diagnosis of patients with high-grade prostatic intraepithelial neoplasia (HGPIN).
TRUSTED_SUSTAINABILITY

Specifications

Antigen ABCA5
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene ABCA5
Gene Accession No. Q8WWZ7
Gene Alias ABC13; Abca5; ATP binding cassette subfamily A member 5; ATP-binding cassette A5; ATP-binding cassette sub-family A member 5; ATP-binding cassette transporter sub-family A member 5; ATP-binding cassette, subfamily A (ABC1), member 5; ATP-binding cassette, sub-family A (ABC1), member 5; ATP-binding cassette, sub-family A , member 5; B930033A02Rik; DKFZp451F117; DKFZp779N2435; EST90625; FLJ16381; Kiaa1888; mKIAA1888
Gene Symbols ABCA5
Host Species Rabbit
Immunogen Synthetic peptide directed towards the C-terminal of human ABCA5 (aa 1296-1345).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23461
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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