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Invitrogen™ ABCA5 Polyclonal Antibody
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Catalog No. PIPA5103633
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PIPA5103633 100 μL
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Catalog No. PIPA5103633 Supplier Invitrogen™ Supplier No. PA5103633
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total ABCA5.

ABCA5 (ATP-binding cassette, sub-family A (ABC1), member 5) is a 1,642 amino acid protein belonging to the ABC transporter superfamily and the ABCA family. The ABC1 subfamily is the only major ABC subfamily exclusive to multicellular eukaryotes. Ubiquitously expressed, with high expression in testis, skeletal muscle, kidney, liver and placenta, ABCA5 is a multi-pass membrane protein that contains two ABC transporter domains and exists as three alternatively spliced isoforms. ABCA5 exhibits membrane subcellular localization and may play a role in processing autolysosomes. Spanning 80 kb, ABCA5 contains 39 exons, with exon 2 containing the putative translation start site. ABCA5 is the first of five ABC1 family members that maps to human chromosome 17q24. ABCA5 is linked to lysosomal diseases and may play a role in tumor development and cardiomyocyte and follicular cell activities. ABCA5 might also be a specific urine marker for diagnosis of patients with high-grade prostatic intraepithelial neoplasia (HGPIN).
TRUSTED_SUSTAINABILITY

Specifications

Antigen ABCA5
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ABCA5
Gene Accession No. Q8CF82, Q8K448, Q8WWZ7
Gene Alias ABC13; Abca5; ATP binding cassette subfamily A member 5; ATP-binding cassette A5; ATP-binding cassette sub-family A member 5; ATP-binding cassette transporter sub-family A member 5; ATP-binding cassette, subfamily A (ABC1), member 5; ATP-binding cassette, sub-family A (ABC1), member 5; ATP-binding cassette, sub-family A , member 5; B930033A02Rik; DKFZp451F117; DKFZp779N2435; EST90625; FLJ16381; Kiaa1888; mKIAA1888
Gene Symbols ABCA5
Host Species Rabbit
Immunogen A synthesized peptide derived from human ABCA5(Accession Q8WWZ7), corresponding to amino acid residues H884-S934.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 217265, 23461, 286970
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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