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Invitrogen™ ABCA7 Polyclonal Antibody
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Catalog No. PIPA569248
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PIPA569248 100 μL
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Catalog No. PIPA569248 Supplier Invitrogen™ Supplier No. PA569248
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Description

Rabbit Polyclonal Antibody

This target displays homology in the following species: Cow: 93%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 93%; Rat: 100%.

ATP-binding cassette (ABC) transporters are an evolutionarily conserved family that use ATP hydrolysis to catalyze the transport of various molecules across cell membranes. They are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). ABCA7, a member of the ABC1 subfamily, is a full-size ABC transporter consisting of two sets of the multiple membrane-spanning domains plus the Walker motifs for the ATP interaction. ABCA7 shows the highest homology to ABCA1, an essential molecule for cholesterol homeostasis. The high expression levels of ABCA7 in peripheral leukocytes, thymus, spleen and bone marrow suggests a role in the immune system lipid homeostasis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ABCA7
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene Abca7
Gene Accession No. Q91V24
Gene Alias ABC 1 antibody; ABC Transporter 1; ABC1; ABC1 antibody; Abc51; Abca7; ABCA-SSN; ABCX; AD9; ATP binding cassette subfamily A member 7; ATP-binding cassette sub-family A member 7; ATP-binding cassette sub-family A member 7; LOW QUALITY PROTEIN: ATP-binding cassette sub-family A member 7; ATP-binding cassette, subfamily A (ABC1), member 7; ATP-binding cassette, sub-family A (ABC1), member 7; ATP-binding cassette, sub-family A, member 7; autoantigen SS-N; CERP; CERP antibody; EC 2.2.1.1; EC 3.6.3; EC 3.6.3.41; FLJ40025; Macrophage ABC transporter; Phospholipid-transporting ATPase ABCA7; phospholipid-transporting ATPase ABCA7; ATP-binding cassette sub-family A member 7
Gene Symbols Abca7
Host Species Rabbit
Immunogen synthetic peptide corresponding to a region of mouse ABCA7.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27403
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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