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Invitrogen™ ABCA7 Polyclonal Antibody
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Catalog No. PIPA575910
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100 μL
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PIPA575910 100 μL
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Catalog No. PIPA575910 Supplier Invitrogen™ Supplier No. PA575910
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

ATP-binding cassette (ABC) transporters are an evolutionarily conserved family that use ATP hydrolysis to catalyze the transport of various molecules across cell membranes. They are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). ABCA7, a member of the ABC1 subfamily, is a full-size ABC transporter consisting of two sets of the multiple membrane-spanning domains plus the Walker motifs for the ATP interaction. ABCA7 shows the highest homology to ABCA1, an essential molecule for cholesterol homeostasis. The high expression levels of ABCA7 in peripheral leukocytes, thymus, spleen and bone marrow suggests a role in the immune system lipid homeostasis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ABCA7
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Abca7
Gene Accession No. Q7TNJ2, Q8IZY2, Q91V24
Gene Alias ABC 1 antibody; ABC Transporter 1; ABC1; ABC1 antibody; Abc51; Abca7; ABCA-SSN; ABCX; AD9; ATP binding cassette subfamily A member 7; ATP-binding cassette sub-family A member 7; ATP-binding cassette sub-family A member 7; LOW QUALITY PROTEIN: ATP-binding cassette sub-family A member 7; ATP-binding cassette, subfamily A (ABC1), member 7; ATP-binding cassette, sub-family A (ABC1), member 7; ATP-binding cassette, sub-family A, member 7; autoantigen SS-N; CERP; CERP antibody; EC 2.2.1.1; EC 3.6.3; EC 3.6.3.41; FLJ40025; Macrophage ABC transporter; Phospholipid-transporting ATPase ABCA7; phospholipid-transporting ATPase ABCA7; ATP-binding cassette sub-family A member 7
Gene Symbols Abca7
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues in Human ABCA7.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10347, 27403, 299609
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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