Invitrogen™ ABCA9 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518953

Catalog No. PIPA518953

Description

This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.

ABCA9 (ATP-binding cassette, sub-family A (ABC1), member 9) is a 1,624 amino acid protein belonging to the ABC transporter superfamily and the ABCA family. The ABC1 subfamily is the only major ABC subfamily exclusive to multicellular eukaryotes. Ubiquitously expressed, with high expression in heart, brain and fetal tissues, ABCA9 is a multi-pass membrane protein that contains two ABC transporter domains and exists as five alternatively spliced isoforms. ABCA9 exhibits membrane subcellular localization and may play a role in monocyte differentiation and lipid homeostasis. ABCA9 is up-regulated during monocyte differentiation into macrophages and down-regulated by cholesterol loading of macrophages. Spanning 85 kb, ABCA9 contains 39 exons, with a non-coding first exon.

Specifications

• Antigen: ABCA9
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ABCA9
• Gene Alias: ABCA9; ATP binding cassette subfamily A member 9; ATP-binding cassette A9; ATP-binding cassette sub-family A member 9; ATP-binding cassette transporter sub-family A member 9; ATP-binding cassette, subfamily A (ABC1), member 9; ATP-binding cassette, sub-family A (ABC1), member 9; D630040K07Rik; DKFZp686F2450; EST640918; MGC75415
• Host Species: Goat
• Purification Method: Ammonium Sulfate Precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 10350
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin)
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q8IUA7
• Gene Symbols: ABCA9
• Immunogen: Synthetic peptide sequence (QRVVQELEMENIQD) corresponding to the internal amino acids of ABCA9 (aa 599-613).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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