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ABCB1 Mouse anti-Human, Clone: OTI2H2, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF809803

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.Specifications
ABCB1 | |
Monoclonal | |
Unconjugated | |
ABCB1 | |
ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 | |
Mouse | |
Affinity Chromatography | |
RUO | |
5243 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Immunohistochemistry (Paraffin), Western Blot | |
OTI2H2 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
P08183 | |
ABCB1 | |
Human recombit protein fragment corresponding to amino acids 995-1280 of human ABCB1 produced in SF9 cell. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG1 |
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