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Invitrogen™ ABCB4 Polyclonal Antibody
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Catalog No. PIPA5100194
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PIPA5100194 100 μL
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Catalog No. PIPA5100194 Supplier Invitrogen™ Supplier No. PA5100194
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MDR3.

The membrane-associated protein encoded ABCB4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ABCB4
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ABCB4
Gene Accession No. P21439, P21440
Gene Alias ABC20; ABC21; ABCB4; ATP binding cassette subfamily B member 4; ATP-binding cassette sub-family B (MDR/TAP) member 4 (P-glycoprotein 3/ multidrug resistance 2; ATP-binding cassette sub-family B (MDR/TAP) member 4 (P-glycoprotein 3/ multidrug resistance 2); ATP-binding cassette sub-family B member 4; ATP-binding cassette, subfamily B (MDR/TAP), member 4; ATP-binding cassette, sub-family B (MDR/TAP), member 4; ATP-binding cassette, sub-family B (MDR/TAP), member 4 (P-glycoprotein 3/ multidrug resistance 2); ATP-binding cassette, subfamily B, member 4; CD243; CLCS; GBD1; GP170; ICP3; MDR1; MDR2; mdr-2; MDR2/3; MDR3; MGC163296; Multidrug resistance protein 2; multidrug resistance protein 3; multiple drug resistance 3; P glycoprotein 2; P glycoprotein 3/multiple drug resistance 3; PFIC-3; P-glycoprotein 2; P-glycoprotein 3; P-glycoprotein 3/ multidrug resistance 2; P-glycoprotein-3/multiple drug resistance-3; P-GP; Pgp3; PGY1; Pgy2; Pgy-2; Pgy3; Phosphatidylcholine translocator ABCB4
Gene Symbols ABCB4
Host Species Rabbit
Immunogen A synthesized peptide derived from human ABCB4(Accession P21439), corresponding to amino acid residues C353-Y403.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18670, 5244
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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