ABCB6Rabbit anti-Canine, Human, Polyclonal, Rockland™

Catalog No.	Quantity
50-199-1881	100 μg

Catalog No. 50-199-1881 Supplier Rockland Immunochemicals Supplier No. 600401945

Description

Rabbit Polyclonal Antibody

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. This affinity-purified antibody is directed against human ABCB6 protein. A BLAST analysis was used to suggest cross reactivity with ABCB6 protein from human and dog based on 100% homology with the immunizing sequence. Expect partial reactivity with ABCB6 from mouse and rat sources based on partial (∼93%, 15/16) sequence homology. Reactivity against homologues from other sources is not known.

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies. This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.

Specifications

• Antigen: ABCB6
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
• Gene: ABCB6
• Gene Accession No.: Q9NP58
• Gene Alias: 1200005B17Rik; ABC; ABC14; Abcb6; ATG9 autophagy related 9 homolog A; ATG9A; ATP binding cassette subfamily B member 6 (Langereis blood group); ATP-binding cassette half-transporter; ATP-binding cassette sub-family B member 6, mitochondrial; ATP-binding cassette, subfamily B (MDR/TAP), member 6; ATP-binding cassette, sub-family B (MDR/TAP), member 6; ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group); ATP-binding cassette, sub-family B, member 6; autophagy related 9A; BOS_2119; DUH3; EST45597; FLJ22414; LAN; MCOPCB7; Mitochondrial ABC transporter 3; mitochondrial ATP-binding cassette sub-family B member 6; Mt-ABC transporter 3; MTABC3; P-glycoprotein-related protein; PRP; PSHK2; Ubiquitously-expressed mammalian ABC half transporter; UMAT
• Gene Symbols: ABCB6
• Host Species: Rabbit
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10058, 478914
• Target Species: Canine, Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid