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Invitrogen™ ABCB7 Polyclonal Antibody
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Catalog No. PIPA5101445
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PIPA5101445 100 μL
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Catalog No. PIPA5101445 Supplier Invitrogen™ Supplier No. PA5101445
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total ABCB7.

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been implicated in X-linked sideroblastic anemia with ataxia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ABCB7
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ABCB7
Gene Accession No. O75027, Q61102
Gene Alias AA517758; ABC transporter 7 protein; ABC7; ABCB7; ASAT; Atm1p; ATP binding cassette subfamily B member 7; ATP-binding cassette 7; ATP-binding cassette sub-family B member 7; ATP-binding cassette sub-family B member 7, mitochondrial; ATP-binding cassette sub-family B member 7, mitochondrial-like protein; ATP-binding cassette transporter 7; ATP-binding cassette, subfamily B (MDR/TAP), member 7; ATP-binding cassette, sub-family B (MDR/TAP), member 7; ATP-binding cassette, sub-family B, member 7; ATP-binding cassette, sub-family B, member 7, mitochondrial; AU019072; EST140535; fc20c02; wu:fc20c02
Gene Symbols ABCB7
Host Species Rabbit
Immunogen A synthesized peptide derived from human ABCB7(Accession O75027), corresponding to amino acid residues F77-Y127.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11306, 22
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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