Invitrogen™ ABCB7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101445

Catalog No. PIPA5101445

Description

Antibody detects endogenous levels of total ABCB7.

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been implicated in X-linked sideroblastic anemia with ataxia.

Specifications

• Antigen: ABCB7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ABCB7
• Gene Alias: AA517758; ABC transporter 7 protein; ABC7; ABCB7; ASAT; Atm1p; ATP binding cassette subfamily B member 7; ATP-binding cassette 7; ATP-binding cassette sub-family B member 7; ATP-binding cassette sub-family B member 7, mitochondrial; ATP-binding cassette sub-family B member 7, mitochondrial-like protein; ATP-binding cassette transporter 7; ATP-binding cassette, subfamily B (MDR/TAP), member 7; ATP-binding cassette, sub-family B (MDR/TAP), member 7; ATP-binding cassette, sub-family B, member 7; ATP-binding cassette, sub-family B, member 7, mitochondrial; AU019072; EST140535; fc20c02; wu:fc20c02
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11306, 22
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O75027, Q61102
• Gene Symbols: ABCB7
• Immunogen: A synthesized peptide derived from human ABCB7(Accession O75027), corresponding to amino acid residues F77-Y127.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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