ABCB8 Polyclonal Antibody, Rockland™

Rabbit Polyclonal Antibody

Supplier:  Rockland Immunochemicals 100401P00S

Catalog No. 50-199-0150

Description

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. A BLAST analysis was used to suggest cross-reactivity with ABCB8 from human, mouse, and rat based on a 100% homology with the immunizing sequence. Reactivity against homologues from other sources is not known. The antibody detects ABCB8 in cell lysates.

This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: ABCB8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ABCB8
• Gene Alias: 4833412N02Rik; AA409895; ABC transporter 8; Abcb8; ATP binding cassette subfamily B member 8; ATP-binding cassette sub-family B member 8, mitochondrial; ATP-binding cassette, subfamily B (MDR/TAP), member 8; ATP-binding cassette, sub-family B (MDR/TAP), member 8; ATP-binding cassette, sub-family B, member 8; BOS_4761; EST328128; hypothetical protein LOC548340; MABC1; M-ABC1; mitochondrial ABC protein; Mitochondrial ATP-binding cassette 1; zgc:113037
• Host Species: Rabbit
• Quantity: 25 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody

• Applications: ELISA, Western Blot
• Concentration: 80 mg/mL
• Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
• Gene Accession No.: Q9NUT2
• Gene Symbols: ABCB8
• Immunogen: ABCB8 was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a internal portion of human ABCB8.
• Regulatory Status: RUO
• Gene ID (Entrez): 11194
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid