Invitrogen™ ABCE1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550287

Catalog No. PA550287

Description

The antibody detects endogenous levels of total ABCE1 protein.

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.

Specifications

• Antigen: ABCE1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ABCE1
• Gene Alias: 2'-5'-oligoadenylate-binding protein; ABC 38; ABC38; ABCE 1; ABCE1; ATP binding cassette subfamily E member 1; ATP-binding cassette sub-family E member 1; ATP-binding cassette, subfamily E (OABP), member 1; ATP-binding cassette, sub-family E (OABP), member 1; ATP-binding cassette, subfamily E, member 1; C79080; HP68; HuHP68; OABP; OK/SW-cl.40; Ribonuclease 4 inhibitor; ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent) inhibitor; ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) inhibitor; RLI; RLI1; RNase 4 inhibitor; RNase L inhibitor; RNase L inhibitor 1; RNASEL1; Rnaseli; RNS41; RNS4I; RNS4l (Eye)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 24015, 6059
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P61221, P61222
• Gene Symbols: ABCE1
• Immunogen: Fusion protein corresponding to a region derived from internal residues of human ATP-binding cassette, sub-family E (OABP), member 1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG