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Invitrogen™ ABCE1 Polyclonal Antibody
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Catalog No. PA550287
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PA550287 100 μL
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Catalog No. PA550287 Supplier Invitrogen™ Supplier No. PA550287
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Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total ABCE1 protein.

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ABCE1
Applications Western Blot
Classification Polyclonal
Concentration 1.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene ABCE1
Gene Accession No. P61221, P61222
Gene Alias 2'-5'-oligoadenylate-binding protein; ABC 38; ABC38; ABCE 1; ABCE1; ATP binding cassette subfamily E member 1; ATP-binding cassette sub-family E member 1; ATP-binding cassette, subfamily E (OABP), member 1; ATP-binding cassette, sub-family E (OABP), member 1; ATP-binding cassette, subfamily E, member 1; C79080; HP68; HuHP68; OABP; OK/SW-cl.40; Ribonuclease 4 inhibitor; ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent) inhibitor; ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) inhibitor; RLI; RLI1; RNase 4 inhibitor; RNase L inhibitor; RNase L inhibitor 1; RNASEL1; Rnaseli; RNS41; RNS4I; RNS4l (Eye)
Gene Symbols ABCE1
Host Species Rabbit
Immunogen Fusion protein corresponding to a region derived from internal residues of human ATP-binding cassette, sub-family E (OABP), member 1.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 24015, 6059
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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