Invitrogen™ ABCE1 Polyclonal Antibody

Catalog No.	Quantity
PIPA578698	100 μg

Catalog No. PIPA578698 Supplier Invitrogen™ Supplier No. PA578698

Description

Rabbit Polyclonal Antibody

Human Bcl-XL shares 97.9% amino acid (aa) sequence identity with both mouse and rat Bcl-XL. Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human HepG2 whole cell lysates, human A431 whole cell lysates, human U2OS whole cell lysates, human Jurkat whole cell lysates, rat brain tissue lysates, mouse brian tissue lysates, mouse 4T1 whole cell lysates, mouse NIH/3T3 whole cell lysates. ICC/IF: Hela cell IP: A431 cell. Flow: U251 cell.

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.

Specifications

• Antigen: ABCE1
• Applications: Flow Cytometry, Immunoprecipitation, Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 500 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 4mg trehalose and no preservative
• Gene: ABCE1
• Gene Accession No.: P61221, P61222
• Gene Alias: 2'-5'-oligoadenylate-binding protein; ABC 38; ABC38; ABCE 1; ABCE1; ATP binding cassette subfamily E member 1; ATP-binding cassette sub-family E member 1; ATP-binding cassette, subfamily E (OABP), member 1; ATP-binding cassette, sub-family E (OABP), member 1; ATP-binding cassette, subfamily E, member 1; C79080; HP68; HuHP68; OABP; OK/SW-cl.40; Ribonuclease 4 inhibitor; ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent) inhibitor; ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) inhibitor; RLI; RLI1; RNase 4 inhibitor; RNase L inhibitor; RNase L inhibitor 1; RNASEL1; Rnaseli; RNS41; RNS4I; RNS4l (Eye)
• Gene Symbols: ABCE1
• Host Species: Rabbit
• Immunogen: E. coli-derived human ABCE1 recombinant protein (Position: K419-D599).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 24015, 361390, 6059
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG