Invitrogen™ ABCF2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA554517

Catalog No. PIPA554517

Description

Immunogen sequence: NHLDIETIDA LADAINEFEG GMMLVSHDFR LIQQVAQEIW VCEKQTITKW PGDILAYKEH LKSKLVDEEP QLTKRTHNVC TLTLASLPRP Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 88%.

OCIAD1 was identified via immunoscreening of an ovarian carcinoma cDNA library from ovarian cancer patients and is expressed in multiple tissues including ovary, placenta, brain, testis, prostate, and mammary gland. Two isoforms of OCIAD1 are known to exist; the shorter isoform is restricted to the central nervous system. OCIAD1 is a transmembrane protein whose overexpression in HEY ovarian cancer cells increased lysophosphatidic acid- (LPA-)induced, but not basal level cell adhesion to extracellular matrix proteins collagen I and laminin10/11. This adhesion is not blocked by LY294002 and GF109203X, suggesting that OCIAD1 does not use protein kinase C and PI3 kinase signaling pathways to exert its effect on adhesion.

Specifications

• Antigen: ABCF2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Abcf2
• Gene Alias: 0710005O05Rik; ABC28; Abcf2; ABC-type transport protein; ATP binding cassette subfamily F member 2; ATP-binding cassette sub-family F member 2; ATP-binding cassette, subfamily F (GCN20), member 2; ATP-binding cassette, sub-family F (GCN20), member 2; developmentally regulated repeat element-containing transcript 3; DKFZp586K1823; Drr3; E430001O06; EST133090; HUSSY18; HUSSY-18; Iron-inhibited ABC transporter 2; M-ABC1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10061
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9UG63
• Gene Symbols: Abcf2
• Immunogen: Recombinant protein corresponding to Human ABCF2. Recombinant protein control fragment (Product #RP-92614).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG