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Invitrogen™ ABCG1 Polyclonal Antibody
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Catalog No. PIPA596284
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100 μL
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PIPA596284 100 μL
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Catalog No. PIPA596284 Supplier Invitrogen™ Supplier No. PA596284
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: AAFSVGTAMN ASSYSAEMTE PKSVCVSVDE VVSSNMEATE TDLLNGHLKK VDNNLTEAQR FSSLPRRAAV NIEFRDLSYS VPEGPWWRKK GYKTLLKGIS GKFNSGELVA IMGPS Positive Samples: SH-SY5Y, A-549, mouse lung, rat lung; Cellular Location: Endoplasmic reticulum membrane, Golgi apparatus membrane, Multi-pass membrane protein.

ATP-binding cassette (ABC) transporter genes are involved in the regulation of the amount of dietary cholesterol retained in the body. The ABC transporter ABCG1 (ABC8) is expressed on the cell surface and in intracellular compartments of cholesterol-laden macrophages and is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. In contrast, lipid efflux in cholesterol-laden macrophages, mediated by the cholesterol acceptor HDL(3), suppresses the expression of ABCG1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ABCG1
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.66 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
Gene ABCG1
Gene Accession No. P45844, Q64343
Gene Alias ABC transporter 8; ABC8; ABCG1; ATP binding cassette subfamily G member 1; ATP-binding cassette 8; ATP-binding cassette sub-family G member 1; ATP-binding cassette transporter 8; ATP-binding cassette transporter member 1 of subfamily G; ATP-binding cassette, subfamily G (WHITE), member 1; ATP-binding cassette, sub-family G (WHITE), member 1; ATP-binding cassette, subfamily G, member 1; AW413978; homolog of Drosophila white; I79_011524; MGC34313; White; White protein homolog; white protein homolog (ATP-binding cassette transporter 8); WHITE1; WHT1
Gene Symbols ABCG1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 6-120 of human ABCG1 (NP_0049063).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11307, 85264, 9619
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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