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Invitrogen™ ABCG4 Polyclonal Antibody
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Catalog No. PIPA5140226
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100 μL
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PIPA5140226 100 μL
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Catalog No. PIPA5140226 Supplier Invitrogen™ Supplier No. PA5140226
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Description

Rabbit Polyclonal Antibody

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: MAEKALEAVG CGLGPGAVAM AVTLEDGAEP PVLTTHLKKV ENHITEAQRF SH Highest antigen sequence indentity to the following orthologs: Rat - 98%, Mouse - 100%.

The ABCG4 gene encodes the ATP-binding cassette sub-family G member 4, a protein that is part of the ABC transporter family involved in the transport of various molecules across cellular membranes. ABC transporters play essential roles in lipid transport, drug resistance, and the maintenance of cellular homeostasis. ABCG4, specifically, is known to be involved in the transport of cholesterol and other lipids, influencing lipid homeostasis and potentially impacting processes such as cholesterol efflux and cellular lipid balance. This protein is expressed in specific tissues, including the brain and retina, indicating its role in neuronal lipid metabolism and health. While its exact physiological functions are still being elucidated, alterations in ABCG4 expression or function may be implicated in lipid-related disorders and neurodegenerative diseases, where lipid metabolism plays a crucial part. Research into ABCG4 focuses on understanding its transport mechanisms and potential contributions to pathological states, aiming to develop targeted therapies that address imbalances in lipid and cholesterol metabolism.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ABCG4
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Abcg4
Gene Accession No. Q9H172
Gene Alias 6430517O04Rik; ABCG4; ATP binding cassette subfamily G member 4; ATP-binding cassette sub-family G member 4; ATP-binding cassette, subfamily G (WHITE), member 4; ATP-binding cassette, sub-family G (WHITE), member 4; putative ABC transporter; WHITE2
Gene Symbols Abcg4
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ABCG4. Recombinant protein control fragment (Product #RP-108945).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64137
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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