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Invitrogen™ ABCG5 Polyclonal Antibody
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Catalog No. PA550538
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PA550538 100 μL
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Catalog No. PA550538 Supplier Invitrogen™ Supplier No. PA550538
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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total ABCG5 protein.

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ABCG5
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.7 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene ABCG5
Gene Accession No. Q9H222
Gene Alias Abcg5; ATP binding cassette subfamily G member 5; ATP-binding cassette sub-family G (WHITE) member 5 (sterolin 1); ATP-binding cassette sub-family G member 5; ATP-binding cassette, subfamily G (WHITE), member 5; ATP-binding cassette, sub-family G (WHITE), member 5; ATP-binding cassette, sub-family G (WHITE), member 5 (sterolin 1); ATP-binding cassette, subfamily G, member 5; AW112016; cmp; sterolin 1; sterolin-1; STSL; trac
Gene Symbols ABCG5
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues near the N terminal of human ATP-binding cassette, sub-family G (WHITE), member 5.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64240
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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