Invitrogen™ ABCG5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA553439

Catalog No. PIPA553439

Description

Immunogen sequence: IHQPRSELFQ LFDKIAILSF GELIFCGTPA EMLDFFNDCG YPCPEHSNPF DFYMDLTSVD TQSKEREIET SKRVQMIESA YKKSAICHKT LKNIERMKHL KTLPMVPFKT KDSPGVFSKL GVLL Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 81%.

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia.

Specifications

• Antigen: ABCG5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ABCG5
• Gene Alias: Abcg5; ATP binding cassette subfamily G member 5; ATP-binding cassette sub-family G (WHITE) member 5 (sterolin 1); ATP-binding cassette sub-family G member 5; ATP-binding cassette, subfamily G (WHITE), member 5; ATP-binding cassette, sub-family G (WHITE), member 5; ATP-binding cassette, sub-family G (WHITE), member 5 (sterolin 1); ATP-binding cassette, subfamily G, member 5; AW112016; cmp; sterolin 1; sterolin-1; STSL; trac
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64240
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9H222
• Gene Symbols: ABCG5
• Immunogen: Recombinant protein corresponding to Human ABCG5. Recombinant protein control fragment (Product #RP-91210).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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