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Invitrogen™ ABCG8 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA554024
Description
Immunogen sequence: HMVQYFTAIG YPCPRYSNPA DFYVDLTSID RRSREQELAT REKAQSLAAL FLEKVRDLDD FLWKAETKDL DEDTCVESSV TPLDTNCLPS PTKMPGAVQQ FTTLIRRQIS NDFRDLP Highest antigen sequence identity to the following orthologs: Mouse - 70%, Rat - 74%.
ATP-binding cassette (ABC) transporter genes are involved in the regulation of the amount of dietary cholesterol retained in the body. ABCG8, expressed at high levels in the liver and intestine, normally cooperates with ABCG5 to limit intestinal absorption and promote biliary excretion of sterols. The mutated form of this transporter can lead to sterol accumulation and atherosclerosis or sitosterolemia, a rare autosomal recessive disorder, characterized by hyperabsorption of sterols and the inability to excrete sterols into bile.
Specifications
ABCG8 | |
Polyclonal | |
Unconjugated | |
Abcg8 | |
1300003C16Rik; ABCG8; AI114946; ATP binding cassette subfamily G member 8; ATP-binding cassette sub-family G member 8; ATP-binding cassette, subfamily G (WHITE), member 8; ATP-binding cassette, sub-family G (WHITE), member 8; ATP-binding cassette, subfamily G, member 8; GBD4; MGC142217; sterolin 2; Sterolin2; sterolin-2; STSL | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
64241 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin) | |
0.3 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
Q9H221 | |
Abcg8 | |
Recombinant protein corresponding to Human ABCG8. Recombinant protein control fragment (Product #RP-91216). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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