Invitrogen™ ABCG8 Polyclonal Antibody

Catalog No.	Quantity
APPA6792	100 μL

Catalog No. APPA6792 Supplier Invitrogen™ Supplier No. PA116792

Description

Rabbit Polyclonal Antibody

This antibody does not react with mouse samples and is not recommended for IHC applications.

ATP-binding cassette (ABC) transporter genes are involved in the regulation of the amount of dietary cholesterol retained in the body. ABCG8, expressed at high levels in the liver and intestine, normally cooperates with ABCG5 to limit intestinal absorption and promote biliary excretion of sterols. The mutated form of this transporter can lead to sterol accumulation and atherosclerosis or sitosterolemia, a rare autosomal recessive disorder, characterized by hyperabsorption of sterols and the inability to excrete sterols into bile.

Specifications

• Antigen: ABCG8
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.1% sodium azide
• Gene: Abcg8
• Gene Accession No.: Q9DBM0, Q9H221
• Gene Alias: 1300003C16Rik; ABCG8; AI114946; ATP binding cassette subfamily G member 8; ATP-binding cassette sub-family G member 8; ATP-binding cassette, subfamily G (WHITE), member 8; ATP-binding cassette, sub-family G (WHITE), member 8; ATP-binding cassette, subfamily G, member 8; GBD4; MGC142217; sterolin 2; Sterolin2; sterolin-2; STSL
• Gene Symbols: Abcg8
• Host Species: Rabbit
• Immunogen: A synthetic peptide from the N-terminal region of human ABCG8 protein.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 64241, 67470
• Target Species: Human, Mouse
• Content And Storage: 4°C, do not freeze
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG