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Invitrogen™ ABCG8 Polyclonal Antibody
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Catalog No. PIPA116798
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200 μL
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PIPA116798 200 μL
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Catalog No. PIPA116798 Supplier Invitrogen™ Supplier No. PA116798
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Description

Rabbit Polyclonal Antibody

Longer exposure times are needed to visualize the wild type ABCG8.

ATP-binding cassette (ABC) transporter genes are involved in the regulation of the amount of dietary cholesterol retained in the body. ABCG8, expressed at high levels in the liver and intestine, normally cooperates with ABCG5 to limit intestinal absorption and promote biliary excretion of sterols. The mutated form of this transporter can lead to sterol accumulation and atherosclerosis or sitosterolemia, a rare autosomal recessive disorder, characterized by hyperabsorption of sterols and the inability to excrete sterols into bile.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ABCG8
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation Phosphate, tris citrate with 0.02% sodium azide; pH 7-8
Gene Abcg8
Gene Accession No. Q9DBM0, Q9H221
Gene Alias 1300003C16Rik; ABCG8; AI114946; ATP binding cassette subfamily G member 8; ATP-binding cassette sub-family G member 8; ATP-binding cassette, subfamily G (WHITE), member 8; ATP-binding cassette, sub-family G (WHITE), member 8; ATP-binding cassette, subfamily G, member 8; GBD4; MGC142217; sterolin 2; Sterolin2; sterolin-2; STSL
Gene Symbols Abcg8
Host Species Rabbit
Immunogen A synthetic peptide from the n-terminal region of human ABCG8 protein.
Purification Method Antigen affinity chromatography
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64241, 67470
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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