Invitrogen™ ABHD13 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5103554

Catalog No. PIPA5103554

Description

Antibody detects endogenous levels of total ABHD13.

The α/β hydrolase superfamily comprise diverse members that are involved in important biochemical processes and related to various diseases. They have unrelated sequences, various substrates, and different kinds of catalytic activities, yet they share the same canonical α/β hydrolase fold, which consists of an eightstranded parallel α/β structure. They are also characterized by a catalytic triad composed of a histidine, an acid and a nucleophile. Members of this superfamily are often drug targets for treating diseases, such as diabetes, Alzheimer's disease, obesity and blood clotting disorders. The Ab hydrolase domain containing (ABHD) gene subfamily is comprised of 15 mostly uncharacterized members. Most of which utilize a serine nucleophile to form the G-X-S-X-G nucleophile elbow. ABHD1 plays a role in metabolizing smoking xenobiotics. ABHD2 participates in the development of atherosclerosis. ABHD4 is involved in an alternative synthesis pathway of NAE. Mutations in ABHD5 contribute to Chanarin-Dorfman syndrome. ABDH6 may play a role in nervous system metabolism and signaling. ABHD13 is a 337 amino acid single-pass membrane protein that belongs to the ABHD family.

Specifications

• Antigen: ABHD13
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ABHD13
• Gene Alias: 1110065L07Rik; Abhd13; abhydrolase domain containing 13; abhydrolase domain-containing protein 13; AI463703; AI788994; Alpha/beta hydrolase domain-containing protein 13; bA153I24.2; BEM46L1; C13orf6; Protein ABHD13; RGD1308317; RP11-153I24.2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 68904, 84945
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q7L211, Q80UX8
• Gene Symbols: ABHD13
• Immunogen: A synthesized peptide derived from human ABHD13(Accession Q7L211), corresponding to amino acid residues G154-S204.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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