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Invitrogen™ ABHD13 Polyclonal Antibody
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Catalog No. PIPA5103554
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PIPA5103554 100 μL
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Catalog No. PIPA5103554 Supplier Invitrogen™ Supplier No. PA5103554
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total ABHD13.

The α/β hydrolase superfamily comprise diverse members that are involved in important biochemical processes and related to various diseases. They have unrelated sequences, various substrates, and different kinds of catalytic activities, yet they share the same canonical α/β hydrolase fold, which consists of an eightstranded parallel α/β structure. They are also characterized by a catalytic triad composed of a histidine, an acid and a nucleophile. Members of this superfamily are often drug targets for treating diseases, such as diabetes, Alzheimer's disease, obesity and blood clotting disorders. The Ab hydrolase domain containing (ABHD) gene subfamily is comprised of 15 mostly uncharacterized members. Most of which utilize a serine nucleophile to form the G-X-S-X-G nucleophile elbow. ABHD1 plays a role in metabolizing smoking xenobiotics. ABHD2 participates in the development of atherosclerosis. ABHD4 is involved in an alternative synthesis pathway of NAE. Mutations in ABHD5 contribute to Chanarin-Dorfman syndrome. ABDH6 may play a role in nervous system metabolism and signaling. ABHD13 is a 337 amino acid single-pass membrane protein that belongs to the ABHD family.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ABHD13
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ABHD13
Gene Accession No. Q7L211, Q80UX8
Gene Alias 1110065L07Rik; Abhd13; abhydrolase domain containing 13; abhydrolase domain-containing protein 13; AI463703; AI788994; Alpha/beta hydrolase domain-containing protein 13; bA153I24.2; BEM46L1; C13orf6; Protein ABHD13; RGD1308317; RP11-153I24.2
Gene Symbols ABHD13
Host Species Rabbit
Immunogen A synthesized peptide derived from human ABHD13(Accession Q7L211), corresponding to amino acid residues G154-S204.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 68904, 84945
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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