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Invitrogen™ ABHD3 Polyclonal Antibody
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Catalog No. PIPA5103555
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PIPA5103555 100 μL
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Catalog No. PIPA5103555 Supplier Invitrogen™ Supplier No. PA5103555
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total ABHD3.

The α/β hydrolase superfamily comprise diverse members that are involved in important biochemical processes and related to various diseases. They have unrelated sequences, various substrates, and different kinds of catalytic activities, yet they share the same canonical α/β hydrolase fold, which consists of an eight stranded parallel α/β structure. They are also characterized by a catalytic triad composed of a histidine, an acid and a nucleophile. Members of this superfamily are often drug targets for treating diseases, such as diabetes, Alzheimer's disease, obesity and blood clotting disorders. The α/β hydrolase domain containing (ABHD) gene subfamily is comprised of 15 mostlyuncharacterized members, most of which utilize a serine nucleophile to form the G-X-S-X-G nucleophile elbow. ABHD1 plays a role in metabolizing smoking xenobiotics. ABHD2 participates in the development of atherosclerosis. ABHD3 is a 409 amino acid single-pass type II membrane protein. ABHD4 is involved in an alternative synthesis pathway of NAE (N-acyl ethanolamine). Mutations in ABHD5 contribute to Chanarin-Dorfman syndrome. ABDH6 may play a role in nervous system metabolism and signaling.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ABHD3
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ABHD3
Gene Accession No. Q8WU67, Q91ZH7
Gene Alias AA675331; ABHD3; abhydrolase domain containing 3; abhydrolase domain-containing protein 3; alpha/beta hydrolase domain containing protein 3; LABH3; Lung alpha/beta hydrolase 3; mmLABH3; Phospholipase ABHD3
Gene Symbols ABHD3
Host Species Rabbit
Immunogen A synthesized peptide derived from human ABHD3(Accession Q8WU67), corresponding to amino acid residues Q276-S326.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 106861, 171586
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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