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ABHD4 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501988150
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50-198-8150 100 μL
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Catalog No. 50-198-8150 Supplier Bioss Supplier No. BS7948R
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Rabbit Polyclonal Antibody

The α/β hydrolase superfamily is comprised of diverse members that are involved in important biochemical processes and related to various diseases. They have unrelated sequences, various substrates, and different kinds of catalytic activities, yet they share the same canonical α/β hydrolase fold, which consists of an eight-stranded parallel α/β structure. They are also characterized by a catalytic triad composed of a histidine, an acid and a nucleophile. Members of this superfamily are often drug targets for treating diseases, such as diabetes, Alzheimer′s disease, obesity and blood clotting disorders. ABHD1 plays a role in metabolizing smoking xenobiotics. ABHD2 participates in the development of atherosclerosis. ABHD4 is involved in an alternative synthesis pathway of NAE. ABHD4 is a lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE) which participates in the biosynthesis of N-acyl ethanolamines. Mutations in ABHD5 contribute to Chanarin-Dorfman syndrome. ABDH6 may play a role in nervous system metabolism and signaling. ABHD14A is possibly involved in granule neuron development.

Specifications

Antigen ABHD4
Applications Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene ABHD4
Gene Accession No. Q8TB40
Gene Alias (Lyso)-N-acylphosphatidylethanolamine lipase; 1110035H23Rik; Abh4; Abhd4; abhydrolase domain containing 4; abhydrolase domain containing 4-like; Abhydrolase domain-containing protein 4; AI429574; Alpha/beta hydrolase domain-containing protein 4; Alpha/beta-hydrolase 4; BOS_10170; LOC100356063; lyso-N-acylphosphatidylethanolamine lipase; Protein ABHD4
Gene Symbols ABHD4
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human ABHD4.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 63874
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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