Invitrogen™ ABI2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA595121

Catalog No. PIPA595121

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human 293T whole cell, human Hela whole cell, human K562 whole cell, human SH-SY5Y whole cell, rat brain tissue, rat PC-12 whole cell, mouse brain tissue. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

ABI2 may act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. ABI2 is a part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. It regulates ABL1/c-Abl-mediated phosphorylation of MENA.

Specifications

• Antigen: ABI2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Abi2
• Gene Alias: 8430425M24Rik; Abelson interactor 2; Abi2; abi-2; ABI2B; abl binding protein 3; abl interactor 2; Abl-binding protein 3; AblBP3; abl-interacting protein 1 (SH3-containing protein); abl-interactor 2; abl-interactor protein 2b; AI839867; AIP-1; arg protein tyrosine kinase-binding protein; arg-binding protein 1; ArgBP1; ARGBPIA; argBPIB; C130078H13; SSH3BP2; thyroid hormone responsive protein
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10152, 286928, 329165
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
• Gene Accession No.: P62484, Q9NYB9
• Gene Symbols: Abi2
• Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human ABI2 (158-173aa RFKVSTQNMKMGGLPR).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov