Invitrogen™ Abl2 Monoclonal Antibody (1H1)

Catalog No.	Quantity
PIMA515586	100 μL

Catalog No. PIMA515586 Supplier Invitrogen™ Supplier No. MA515586

Description

Mouse Monoclonal Antibody

MA5-15586 targets ABL2 in indirect ELISA, IF and WB applications and shows reactivity with Human and mouse samples. The MA5-15586 immunogen is purified recombinant fragment of ABL2 expressed in E. Coli. MA5-15586 detects ABL2 which has a predicted molecular weight of approximately 128kDa.

ABL2 (Arg) is an Abl-related non-receptor protein tyrosine kinase that links cell surface receptors to cell proliferation and/or cytoskeletal reorganization. Abl2 encodes a member of the Abelson family of nonreceptor tyrosine protein kinase. The protein is highly similar to the ABL1 protein, including the tyrosine kinase, SH2 and SH3 domains, and has a role in cytoskeletal rearrangements by its C-terminal F-actin- and microtubule-binding sequences. Abl2 is expressed in both normal and tumor cells, and is involved in translocation with the ETV6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

Specifications

• Antigen: Abl2
• Applications: ELISA, Western Blot, Immunocytochemistry
• Classification: Monoclonal
• Clone: 1H1
• Concentration: Conc. Not Determined
• Conjugate: Unconjugated
• Formulation: ascites with 0.03% sodium azide
• Gene: ABL2
• Gene Accession No.: P42684, Q4JIM5
• Gene Alias: AA536808; Abelson murine leukemia viral (v-abl) oncogene homolog 2; abelson murine leukemia viral oncogene homolog 2; Abelson tyrosine-protein kinase 2; Abelson-related gene protein; ABL proto-oncogene 2, non-receptor tyrosine kinase; Abl1-related gene product; abl2; ABLL; ARG; arg tyrosine kinase; c-abl oncogene 2, non-receptor tyrosine kinase; FLJ22224; FLJ31718; FLJ41441; tyrosine kinase ARG; tyrosine-protein kinase ABL2; Tyrosine-protein kinase ARG; v-abl Abelson murine leukemia viral oncogene 2; v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene); v-abl Abelson murine leukemia viral oncogene homolog 2; v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)
• Gene Symbols: ABL2
• Host Species: Mouse
• Immunogen: Purified recombinant fragment of ABL2 expressed in E. Coli.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 11352, 27
• Target Species: Human, Mouse
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov