Invitrogen™ ABO Recombinant Rabbit Monoclonal Antibody (2V4R0)

Catalog No.	Quantity
PIMA535675	100 μL

Catalog No. PIMA535675 Supplier Invitrogen™ Supplier No. MA535675

Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: MAEVLRTLAG KPKCHALRPM ILFLIMLVLV LFGYGVLSPR SLMPGSLERG FCMAVREPDH LQRVSLPRMV YPQPKVLTPC RKDVLVVTPW LAPIVWEGTF.

Histo-blood group ABO system transferase (NAGAT) is a member of the glycosyltransferase 6 family of proteins and the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B and H; the NAGAT protein functions as the basis of this group. A, B and AB individuals express a glycosyltransferase activity converting the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), while O individuals do not express this glycosyltransferase activity. The B phenotype of NAGAT differs from the A form by a few residue substitutions, whereas the O form is a result of a single base frame-shift deletion in the N-terminal extremity of the gene. The NAGAT protein localizes to the Golgi apparatus and its conserved DXD motif functions in cofactor binding.

Specifications

• Antigen: ABO
• Applications: ELISA, Western Blot
• Classification: Recombinant Monoclonal
• Clone: 2V4R0
• Concentration: 1.47 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: ABO
• Gene Accession No.: P16442
• Gene Alias: a transferase; A1-specific alpha 1-3-N-acetylgalactosaminyltransferase; A3GALNT; A3GALT1; ABO; ABO A3 transferase; ABO blood group (alpha 1-3-N-acetylgalactosaminyltransferase, alpha 1-3-galactosyltransferase); ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase, transferase B, alpha 1-3-galactosyltransferase); ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase); ABO glycosyltransferase; ABO weak transfer; Abo2; B (A) alpha 1; B blood group galactosyltransferase; b transferase; B(A) alpha-1,3-galactosyltransferase; BGAT; blood group A glycosyltransferase 2; Cis-AB transferase; cis-AB transferase 2; fucosylglycoprotein; fucosylglycoprotein 3-alpha-galactosyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form; Glycoprotein-fucosylgalactoside alpha-galactosyltransferase; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase; glycosyltransferase A; glycosyltransferase B; GTB; Histo-blood group A transferase; histo-blood group A2 transferase; histo-blood group ABO system transferase; Histo-blood group ABO system transferase 2; histo-blood group B transferase; NAGAT; NAGAT 2; putative blood group A transferase T2; Transferase; transferase A; transferase B, alpha 1-3-galactosyltransferase)
• Gene Symbols: ABO
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BGAT (P16442).
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 28
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG