ABO Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA5106879

Catalog No. PIPA5106879

Description

Antibody detects endogenous levels of total ABO.

Histo-blood group ABO system transferase (NAGAT) is a member of the glycosyltransferase 6 family of proteins and the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B and H; the NAGAT protein functions as the basis of this group. A, B and AB individuals express a glycosyltransferase activity converting the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), while O individuals do not express this glycosyltransferase activity. The B phenotype of NAGAT differs from the A form by a few residue substitutions, whereas the O form is a result of a single base frame-shift deletion in the N-terminal extremity of the gene. The NAGAT protein localizes to the Golgi apparatus and its conserved DXD motif functions in cofactor binding.

Specifications

• Antigen: ABO
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ABO
• Gene Alias: a transferase; A1-specific alpha 1-3-N-acetylgalactosaminyltransferase; A3GALNT; A3GALT1; ABO; ABO A3 transferase; ABO blood group (alpha 1-3-N-acetylgalactosaminyltransferase, alpha 1-3-galactosyltransferase); ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase, transferase B, alpha 1-3-galactosyltransferase); ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase); ABO glycosyltransferase; ABO weak transfer; Abo2; B (A) alpha 1; B blood group galactosyltransferase; b transferase; B(A) alpha-1,3-galactosyltransferase; BGAT; blood group A glycosyltransferase 2; Cis-AB transferase; cis-AB transferase 2; fucosylglycoprotein; fucosylglycoprotein 3-alpha-galactosyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form; Glycoprotein-fucosylgalactoside alpha-galactosyltransferase; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase; glycosyltransferase A; glycosyltransferase B; GTB; Histo-blood group A transferase; histo-blood group A2 transferase; histo-blood group ABO system transferase; Histo-blood group ABO system transferase 2; histo-blood group B transferase; NAGAT; NAGAT 2; putative blood group A transferase T2; Transferase; transferase A; transferase B, alpha 1-3-galactosyltransferase)
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100301568, 28, 80908
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P16442, P38649, Q9ET32
• Gene Symbols: ABO
• Immunogen: A synthesized peptide derived from human ABO(Accession P16442), corresponding to amino acid residues G33-D83.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov