Tocris™ AC 186

Potent and selective ERbeta agonist; neuroprotective

Manufacturer: Tocris™ 5053/50

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Catalog No. 50-535-0RD

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For Research Use Only


    Specifications

    Description AC 186
    Molecular Weight 306.32
    Purity >99
    Quantity 50mg
    Product Type AC 186

    Potent and selective ERβ agonist (EC50 values are 6 and 5000nM for ERβ and ERα respectively). Exhibits gender selective neuroprotective effects in a male rat model of Parkinson's disease. Decreases Aβ levels in combination with ACP-105 in a rat model of Alzheimer's disease.

    • Chemical Name: 4-[4,4-Difluoro-1-(2-fluorophenyl)cyclohexyl]phenol
    • Formula: C18H17F3O
    • CAS Number: 1421854-16-1
    • Solubility: Soluble to 100mM in DMSO
    • Purity: >99

  • Description & Specifications

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