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Tocris Bioscience™ AC 265347
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Catalog No. 616550
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Catalog No. Quantity
61-655-0 50 mg
61-651-0 10 mg
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Catalog No. 61-655-0 Supplier Tocris Bioscience™ Supplier No. 6165/50
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Description

CaSR biased allosteric modulator

AC 265347 is a CaSR biased allosteric modulator (pEC50 = 7.8-8.1). Calcimimetic. Displays ability to bias signalling towards the accumulation of pERK1/2 and IP1. Reduces parathyroid hormone (PTH) levels in rat serum without inducing the release of calcitonin. Exhibits no significant activation of human GABAB or type I PTH receptors. Orally active.

Specifications

Chemical Name or Material α-(2,4-Dimethylphenyl)-α-methyl-2-benzothiazolemethanol
CAS 1253901-26-6
Assay Percent Range >99%
Quantity 50 mg
Molecular Formula C17H17NOS
Formula Weight Observed MW: 283.39
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