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Description
This gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone. [provided by RefSeq]
Specifications
Specifications
| Antigen | ACAT1 |
| Applications | ELISA, Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Monoclonal |
| Clone | AT2C5 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against partial recombinant human ACAT1. |
| Dilution | ELISA Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) Western Blot (1:1000) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS, pH 7.4 (0.09% sodium azide) |
| Gene Alias | ACAT/MAT/T2/THIL |
| Gene Symbols | ACAT1 |
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