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Invitrogen™ SOAT1 Polyclonal Antibody
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Catalog No. APSA6811
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100 μL
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APSA6811 100 μL
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Catalog No. APSA6811 Supplier Invitrogen™ Supplier No. PA316811
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Description

Rabbit Polyclonal Antibody

Suggested positive control: CHO cell lysate.

SOAT1 (sterol O-acyltransferase-1), also designated ACAT1, is a homotetra-meric enzyme that catalyzes the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A (acyl-CoA). The gene encoding human SOAT1 maps to chromosome 1 and is expressed as a protein that localizes to the endoplasmic reticulum (ER) in several tissues, including liver, kidney, adrenal glands and macrophages. SOAT1 is involved in cellular cholesterol homeostasis as well as in foam cell formation and the subsequent progression of atherosclerosis. Several SOAT inhibitors have been developed for the treatment of atherosclerosis. SOAT2 (sterol O-acyltransferase-2), also known as ACAT2 (acyl-CoA:cholesterol acyltransferase-2), participates in lipo-protein assembly, catalyzing cholesterol esterification in mammalian cells. SOAT2 is an integral membrane protein that localizes to the endoplasmic reticulum of human intestinal cells. SOAT2 deficiency contributes to severe mental retardation and hypotonus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SOAT1
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Whole serum with 0.02% sodium azide
Gene SOAT1
Gene Accession No. P35610, Q60457, Q61263
Gene Alias 8430426K15Rik; Acact; ACACT1; Acat; ACAT1; ACAT-1; acyl coenzyme A:cholesterol acyltransferase 1; acyl-coenzyme A:cholesterol acyltransferase 1; adrenocortical lipid depletion; ald; AW550831; cholesterol acyltransferase 1; hid; SOAT; SOAT1; STAT; sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1; sterol O-acyltransferase 1
Gene Symbols SOAT1
Host Species Rabbit
Immunogen A fusion protein construct that contains the N-terminal region of human SOAT1.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100689317, 20652, 6646
Target Species Hamster, Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer and Reproductive Harm - www.P65Warnings.ca.gov
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