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Invitrogen™ ACAT2 Recombinant Rabbit Monoclonal Antibody (6Z5L1)
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Catalog No. PIMA542668
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100 μL
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PIMA542668 100 μL
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Catalog No. PIMA542668 Supplier Invitrogen™ Supplier No. MA542668
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Description

Rabbit Recombinant Monoclonal Antibody

Positive test controls include: HeLa, SW620, HepG2, Mouse liver, Mouse brain, Mouse kidney, Rat brain, Rat kidney. The target is usually found in the following locations: Cytoplasm. Immunogen sequence: GLTDAFHNCH MGITAENVAK KWQVSREDQD KVAVLSQNRT ENAQKAGHFD KEIVPVLVST RKGLIEVKTD EFPRHGSNIE AMSKLKPYFL TDGTGTVTPA N.

This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ACAT2
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 6Z5L1
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Acat2
Gene Accession No. Q5XI22, Q8CAY6, Q9BWD1
Gene Alias Ab2-076; Acat2; Acat3; acetoacetyl Coenzyme A thiolase; acetyl-CoA acetyltransferase 2; acetyl-CoA acetyltransferase, cytosolic; Acetyl-CoA transferase-like protein; acetyl-Coenzyme A acetyltransferase 2; acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase); acetyl-Coenzyme A acetyltransferase 3; ACTL; AE1; AW742799; BND3; CD233; cytosolic acetoacetyl-CoA thiolase; DI; EMPB3; EPB3; FR; RTA1A; SW; t-complex protein 1, related sequence 1; Tcp1-rs1; Tcp-1x; WD; WD1; WR
Gene Symbols Acat2
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 150-250 of human ACAT2 (Q9BWD1).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 110460, 308100, 39
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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