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ACC1/ACC-alpha Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501558957
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50-155-8957 20 μL
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Catalog No. 50-155-8957 Supplier Bethyl Laboratories, Inc Supplier No. A300987AT
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Sheep and Bovine

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5′ sequence and encoding distinct isoforms have been found for this gene.

Specifications

Antigen ACC1/ACC-alpha
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene ACACA
Gene Accession No. Q13085
Gene Alias ACC-alpha; acetyl-CoA carboxylase 1; acetyl-Coenzyme A carboxylase alpha
Gene Symbols ACACA
Host Species Rabbit
Immunogen Between 2333 and C-term
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 31
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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